Tumores faciales en un paciente con múltiples neoplasias / Facial tumours in a patient with multiple neoplasms

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Estudio prospectivo de la hiperpigmentación del área genital en recién nacidos españoles: frecuencia y factores predisponentes / Prospective study of hyperpigmentation of the genital area in Spanish newborns: frequency and predisposing factors

Realizamos un estudio prospectivo de 1.000 recién nacidos vistos en las primeras 72 horas de vida en el Área Sanitaria de Ferrol (noroeste de España)con el objetivo de conocer la prevalencia de la hiperpigmentación del área genital y ver como influyen, en su aparición, los factores neonatales y maternos, el momento de exploración y la modalidad de parto. La frecuencia de la hiperpigmentación genital fue del 15,3%. Encontramos una prevalencia superior en los neonatos no caucásicos (p = 0,000) de sexo masculino (p = 0,000), con mancha mongólica (p = 0,000), nacidos por vía vaginal (p =0,030) y con madre menor de 30 años (p = 0,006) y con al menos 2 gestaciones previas (p = 0,015) (AU)

We performed a prospective study of 1,000 neonates investigated in the first 72 hours of life in the Health Area of Ferrol (northwest of Spain), in order to assess the prevalence of hyperpigmentation of the genital area, the influence of different maternal and neonatal parameters, day of neonatalexploration and type of delivery. Overall frequency of hyperpigmentation was 15.3%. We found a higher prevalence of this dermatosis in non-Caucasian infants (p = 0.000) of male sex (p = 0.000), with Mongolian spot (p = 0.000), vaginal delivery (p = 0.030), maternal age below 30 years (p =0.006) and at least two previous pregnancies (p = 0.015) (AU)

Lamotrigine induced subacute cutaneous lupus erythematous.

A 48-year-old woman developed drug-induced subacute lupus erythematosus while taking lamotrigine. The eruption resolved after discontinuance of lamotrigine, suggesting this drug as the cause.

Influencia de los factores neonatales y maternos en la prevalencia de vérnix caseosa / Influence of Neonatal and Maternal Factors on the Prevalence of Vernix Caseosa

Al nacimiento la vérnix caseosa puede cubrir toda la superficie corporal o acumularse sólo en la espalda y los pliegues. En los últimos años ha aumentado el interés por su composición, funciones y aplicaciones en la edad adulta. Nuestro objetivo fue conocer la prevalencia de la vérnix caseosa en los recién nacidos del Área Sanitaria de Ferrol, y ver cómo repercutían los parámetros neonatales y maternos en su desarrollo. Realizamos un estudio prospectivo de 1.000 recién nacidos vistos en los primeros tres días de vida en nuestro hospital. Encontramos vérnix caseosa en el 49,2% de los neonatos. El perfil clínico de presencia de vérnix caseosa sería: recién nacido de sexo femenino, sano, a término, con peso elevado producto de una gestante no primigesta, con ingesta de fármacos y suplementos dietéticos durante el embarazo sometida a un parto eutócico. Existe relación entre ausencia de vérnix caseosa y la presencia de descamación fisiológica y de eritema tóxico neonatal (AU)

At birth, vernix caseosa can cover the whole body surface or accumulate only on the back and in the skin folds. Interest in its composition and function and its possible applications in adults has increased in recent years. The objective of this study was to determine the prevalence of vernix caseosa in newborn infants in the health care area of Ferrol, Spain, and to assess its relationship with neonatal and maternal factors. We performed a prospective study of 1000 newborns seen within the first 3days of life in our hospital. Vernix caseosa was observed in 42.9% of cases. The clinical profile associated with the presence of vernix caseosa was the following: healthy newborn girl with a high birth weight, born at term by normal vaginal delivery to a multiparous mother who had received medication and dietary supplements during pregnancy. The absence of vernix caseosa was associated with the presence of physiological scaling of the newborn and erythema toxicum neonatorum (AU)

[Influence of neonatal and maternal factors on the prevalence of vernix caseosa]. / Influencia de los factores neonatales y maternos en la prevalencia de vérnix caseosa.

At birth, vernix caseosa can cover the whole body surface or accumulate only on the back and in the skin folds. Interest in its composition and function and its possible applications in adults has increased in recent years. The objective of this study was to determine the prevalence of vernix caseosa in newborn infants in the health care area of Ferrol, Spain, and to assess its relationship with neonatal and maternal factors. We performed a prospective study of 1000 newborns seen within the first 3 days of life in our hospital. Vernix caseosa was observed in 42.9% of cases. The clinical profile associated with the presence of vernix caseosa was the following: healthy newborn girl with a high birth weight, born at term by normal vaginal delivery to a multiparous mother who had received medication and dietary supplements during pregnancy. The absence of vernix caseosa was associated with the presence of physiological scaling of the newborn and erythema toxicum neonatorum.

Queratosis seborreicas eruptivas y transitorias desencadenadas por una dermatitis seborreica / Transient eruptive seborrheic keratoses triggered by seborrheic dermatitis

Los acantomas posteczema, también llamados queratosis seborreicas eruptivas transitorias, fueron descritos por Williams en 1956. Son lesiones similares a queratosis seborreicas que aparecen en áreas afectas por dermatosis inflamatorias y que se resuelven espontáneamente en los seis primeros meses tras la curación del proceso cutáneo de base. Con frecuencia se confunde esta entidad con el signo de Leser-Trélat. Presentamos los casos dedos pacientes con acantomas posteczema que aparecieron tras un brote de dermatitis seborreica (AU)

Posteczema acanthomas, also called transient eruptive seborrheic keratoses, were first described by Williams in 1956. They are seborrheic keratoseslikelesions, usually involving areas affected by inflammatory dermatoses, and they tend to regress spontaneously in the following six months after thehealing of the primary cutaneous condition. They are often misdiagnosed as the Leser-Trélat sign. We report two cases of eruptive posteczema acanthomasfollowing an exacerbation of seborrheic dermatitis (AU)

Prevalencia y características clínicas de los nevos melanocíticos congénitos en 1.000 recién nacidos españoles / Prevalence and Clinical Features of Congenital Melanocytic Nevi in 1, 000 Spanish Newborns

Introducción: El nevo melanocítico congénito es una proliferación melanocítica benigna presente al nacimiento o en los primeros meses de vida. Aunque es una lesión común, hay pocos estudios en nuestro entorno que analicen su frecuencia. El objetivo de nuestro estudio es conocer su prevalencia y las localizaciones más frecuentes en los recién nacidos de nuestra área sanitaria, y analizar la influencia de los factores neonatales y maternos en el desarrollo de estas lesiones. Pacientes y métodos: Realizamos un estudio prospectivo de 1.000 neonatos consecutivos vistos en las primeras 72 horas de vida en la consulta de Perinatología del Servicio de Pediatría de nuestro hospital (Hospital Arquitecto Marcide, Ferrol, España). En cada caso se recogieron datos referentes a diferentes parámetros maternos y neonatales, y la presencia, el tamaño y la localización de los nevos melanocíticos congénitos. Resultados: Catorce neonatos (el 1,4% de los neonatos incluidos) presentaban al menos un nevo melanocítico congénito. Doce eran caucasianos y 2 árabes. Respecto al sexo, 10 recién nacidos eran de sexo femenino y 4 de sexo masculino. En todos los casos presentaba solo un nevo melanocítico. Ocho se localizaban en el tronco, 2 en el área facial, 2 en las extremidades superiores y 2 en las inferiores. El 50% de los nevos melanocíticos congénitos tenían un diámetro inferior a 1,5cm y la otra mitad entre 1,5 y 3,5cm. Conclusiones: Existe una mayor prevalencia de nevos melanocíticos en los recién nacidos pretérmino, de sexo femenino y no caucasianos. La edad materna, el número de gestaciones previas y el peso al nacimiento no parecen influir en su aparición (AU)

Background: Congenital melanocytic nevus is a benign proliferation of melanocytes that is present at birth or develops in the first months of life. Although such lesions are common, few studies have analyzed their prevalence in Spain. Objectives: The aim of this study was to define the prevalence and most frequent anatomical areas affected by congenital melanocytic nevi in our health service area. We also analyzed the influence of maternal and neonatal factors in the development of these lesions. Patients and methods: We performed a prospective study of 1000 consecutive neonates seen in the first 72hours of life in the perinatology clinic of the Pediatrics Department of Hospital Arquitecto Marcide in Ferrol, Spain, recording specific maternal and neonatal variables and the size and site of congenital melanocytic nevi if present. Results: Fourteen infants (10 girls and 4 boys; 12 white European, 2 North African; 1.4% of the study population) presented at least 1 melanocytic nevus. None had more than 1 lesion. Eight of the nevi were located on the trunk, 2 on the face, 2 on the upper limbs, and 2 on the lower limbs. The diameter of the lesions was less than 1.5cm in half of cases and between 1.5 and 3.5cm in the remainder. Conclusions: There was a higher prevalence of congenital melanocytic nevi in preterm infants, females, and nonwhite infants. Maternal age, number of previous pregnancies, and birth weight do not appear to influence the prevalence of these lesions (AU)

[Prevalence and clinical features of congenital melanocytic nevi in 1,000 Spanish newborns]. / Prevalencia y características clínicas de los nevos melanocíticos congénitos en 1.000 recién nacidos españoles.

BACKGROUND: Congenital melanocytic nevus is a benign proliferation of melanocytes that is present at birth or develops in the first months of life. Although such lesions are common, few studies have analyzed their prevalence in Spain. OBJECTIVES: The aim of this study was to define the prevalence and most frequent anatomical areas affected by congenital melanocytic nevi in our health service area. We also analyzed the influence of maternal and neonatal factors in the development of these lesions. PATIENTS AND METHODS: We performed a prospective study of 1000 consecutive neonates seen in the first 72hours of life in the perinatology clinic of the Pediatrics Department of Hospital Arquitecto Marcide in Ferrol, Spain, recording specific maternal and neonatal variables and the size and site of congenital melanocytic nevi if present. RESULTS: Fourteen infants (10 girls and 4 boys; 12 white European, 2 North African; 1.4% of the study population) presented at least 1 melanocytic nevus. None had more than 1 lesion. Eight of the nevi were located on the trunk, 2 on the face, 2 on the upper limbs, and 2 on the lower limbs. The diameter of the lesions was less than 1.5 cm in half of cases and between 1.5 and 3.5 cm in the remainder. CONCLUSIONS: There was a higher prevalence of congenital melanocytic nevi in preterm infants, females, and nonwhite infants. Maternal age, number of previous pregnancies, and birth weight do not appear to influence the prevalence of these lesions.

Blaschkitis del adulto (liquen estriado) en paciente tratado con adalimumab / Adult Blaschkitis (Lichen Striatus) in a Patient Treated with Adalimumab

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